https://hdl.handle.net/10807/209 Wed, 03 Jun 2026 23:45:37 GMT 2026-06-03T23:45:37Z https://hdl.handle.net/10807/337642 Titolo: "At Least the Second Plate": rethinking nutritional care in the geriatric unit Autori: Marzetti, Emanuele; Calvani, Riccardo; Coelho-Junior, Hélio Jose Abstract: Adequate nutritional care is important to reduce adverse outcomes in hospitalized older adults. However, achieving adequate nutritional intake in geriatric units is challenging due to appetite-related disorders, chronic diseases, anabolic resistance, and limitations associated with oral nutritional supplementation. In this context, healthcare professionals often encourage patients to consume "at least the second plate," which is usually centered on protein-rich foods, as an attempt to preserve muscle mass and support recovery. However, it remains unclear whether this strategy alone is sufficient to meet the nutritional needs of hospitalized older adults. In this manuscript, we discuss the limitations of focusing predominantly on protein-rich meals and emphasize the importance of adequate energy intake for muscle preservation and overall recovery in geriatric inpatients. Thu, 01 Jan 2026 00:00:00 GMT https://hdl.handle.net/10807/337642 2026-01-01T00:00:00Z https://hdl.handle.net/10807/337556 Titolo: From surface to core: does better cooling make a difference after cardiac arrest? Autori: Sandroni C.; Delamarre L.; Nolan J. P. Abstract: Hypoxic–ischaemic brain injury remains the leading cause of death after out-of-hospital cardiac arrest. Temperature control strategies have evolved substantially following the TTM-2 trial, which showed no survival benefit of hypothermia over active normothermia with fever prevention. In this editorial, Sandroni et al. discuss a post hoc analysis of the TTM-2 trial comparing intravascular cooling (IC) and surface cooling (SFC) in patients receiving therapeutic hypothermia. IC achieved superior temperature control, with faster attainment of target temperature, less time outside the therapeutic range, fewer episodes of post-treatment fever, and reduced overcooling compared with SFC. Although unadjusted analyses suggested improved neurological outcomes with IC, this association disappeared after inverse probability treatment weighting adjustment, indicating no statistically significant improvement in six-month neurological survival. The authors highlight important limitations, including the post hoc design and incomplete data regarding device selection. Experimental studies suggest that earlier and faster cooling may enhance neuroprotection, but clinical implementation remains substantially slower than in animal models. Current evidence therefore continues to support guideline recommendations favoring active normothermia and fever prevention rather than routine hypothermia after cardiac arrest. Ongoing trials such as STEPCARE may clarify optimal temperature management strategies in this population. Wed, 01 Jan 2025 00:00:00 GMT https://hdl.handle.net/10807/337556 2025-01-01T00:00:00Z https://hdl.handle.net/10807/337459 Titolo: Editoriale - Affrontare il cambiamento climatico. Metodo, ragioni e procedure per la definizione di politiche science-based Autori: Tallacchini, M; Petteruti, C; Ragone G Abstract: Nel cammino che la comunità internazionale è chiamata a percorrere verso l'ambizioso obiettivo di governo del cambiamento climatico, con azioni di mitigazione e adattamento al cambio del clima, un aspetto decisivo è quello che concerne l’individuazione di adeguati sistemi di Science-for-Policy. Senza il rafforzamento e l’affinamento dei meccanismi che consentono un utilizzo strutturato, consapevole e trasparente delle conoscenze scientifiche a supporto delle decisioni pubbliche, il riconoscimento della centralità della «best available science for effective climate action and policymaking» è destinata a rimanere clausola di stile. Thu, 01 Jan 2026 00:00:00 GMT https://hdl.handle.net/10807/337459 2026-01-01T00:00:00Z https://hdl.handle.net/10807/337437 Titolo: Waking up sooner: EEG-guided early cessation of sedation after cardiac arrest Autori: Sandroni C.; Moseby-Knappe M. Thu, 01 Jan 2026 00:00:00 GMT https://hdl.handle.net/10807/337437 2026-01-01T00:00:00Z