https://hdl.handle.net/10807/1 Wed, 26 Aug 2026 14:51:27 GMT 2026-08-26T14:51:27Z https://hdl.handle.net/10807/345148 Titolo: Reply from Authors re: Manfred P. Wirth and Michael Froehner. Radical Prostatectomy-Only Centers: The Future in Genitourinary Surgery? Eur Urol 2010;57:953-4 Autori: Coelho R. F.; Rocco B.; Patel V. R. Abstract: N/A Fri, 01 Jan 2010 00:00:00 GMT https://hdl.handle.net/10807/345148 2010-01-01T00:00:00Z https://hdl.handle.net/10807/345147 Titolo: Reply from authors re: Khurshid R. Ghani, Mani Menon. Posterior reconstruction: Weighing the evidence. Eur Urol 2012;62:791-3: The posterior reconstruction debate Autori: Rocco B.; Cozzi G.; Spinelli M. G.; Coelho R. F.; Santoro L.; Patel V. R.; Rocco F. Abstract: N/A Sun, 01 Jan 2012 00:00:00 GMT https://hdl.handle.net/10807/345147 2012-01-01T00:00:00Z https://hdl.handle.net/10807/345146 Titolo: Restoration of Posterior Aspect of Rhabdosphincter Shortens Continence Time After Radical Retropubic Prostatectomy Autori: Rocco F.; Carmignani L.; Acquati P.; Gadda F.; Dell'Orto P.; Rocco B.; Bozzini G.; Gazzano G.; Morabito A. Abstract: Purpose: Prolonged postoperative incontinence is a major drawback of RRP. Age, scars in the rhabdosphincter, nonnerve sparing surgery and postoperative sphincter insufficiency can cause temporary or definitive urinary incontinence. We believe that sphincter deficiency is the main cause of early incontinence. Urinary leakage results from the shortening of anatomical and functional sphincter length due to caudal retraction of the urethral sphincteric complex and disruption of the median posterior fibrous raphe. We describe a modification of the Walsh RRP that overcomes caudal retraction, reconstructs the posterior fibrous raphe and decreases time to continence. The primary study end point was early continence rate assessment. Long-term continence (1 year) and erectile function assessment were secondary end points. Materials and Methods: To avoid caudal retraction of the urethrosphincteric complex, before completing the vesicourethral anastomosis the posterior semicircumference of the sphincter is joined to the residuum of Denonvilliers' fascia and fixed to the posterior bladder wall 1 to 2 cm cranial and dorsal to the new bladder neck. Vesicourethral anastomosis is subsequently performed with care taken not to involve the neurovascular bundles. A total of 161 patients with clinically confined disease underwent modified RRP (group 1). They were compared with a historical series of 50 patients who underwent standard RRP (group 2). Early continence was defined as no pad use but patients using 1 diaper were also considered continent. Continence, assessed prospectively as the number of pads daily, was evaluated 3, 30 and 90 days, and 1 year after catheter removal. The continence state was assessed by a multivariate logistic model. Erectile function was evaluated using the International Index of Erectile Function questionnaire preoperatively and after 18 months in patients younger than 65 years who underwent nerve sparing surgery. Results: In group 1, 116 (72%), 127 (78.8%) and 139 patients (86.3%) were continent 3, 30 and 90 days after catheter removal compared with 7 (14%), 15 (30%) and 23 (46%), respectively, in group 2. One-year continence rates were 96% and 90%, respectively. Erectile function was similar in groups 1 and 2 (46% and 42%, respectively). Multivariate analysis showed that continence was significantly influenced by operation type, stage and patient age. Conclusions: Careful reconstruction of the posterior aspect of the rhabdosphincter markedly shortens time to continence. © 2006 American Urological Association. Sun, 01 Jan 2006 00:00:00 GMT https://hdl.handle.net/10807/345146 2006-01-01T00:00:00Z https://hdl.handle.net/10807/345145 Titolo: ALT-tomato: a process-based model for Alternaria disease complex addressing mycotoxin risk Autori: Salotti I.; Camardo Leggieri M.; Battilani P. Abstract: The Alternaria disease complex has emerged as a major concern in tomato cropping systems, posing significant threats to both tomato production and human health due to the co-occurrence of multiple species on the same plants and the production of mycotoxins. Predictive tools are instrumental in advancing food security and mitigating risks to food safety. Therefore, this study aimed to synthesize current knowledge on Alternaria spp. affecting tomato and develop a mechanistic, weather-driven model capable of predicting both epidemics and mycotoxin contamination. A systematic literature review was conducted to compile quantitative information on the ecology, biology, epidemiology, and mycotoxin production of Alternaria species associated with the disease complex. These data were used to construct a logical and mathematical framework describing interactions among major Alternaria species, tomato, and environmental drivers. The resulting model comprises interconnected compartments representing: (i) conidia production from overwintering and in-season sources, (ii) conidia dispersal, (iii) infection by conidia, (iv) symptom development, and (v) mycotoxin (alternariol, alternariol monomethyl ether, and tenuazonic acid) production and accumulation within tomato fruit tissues. Model parameterization was performed for three major species affecting tomato (A. alternata, A. solani, and A. tenuissima). Model validation using eight epidemics recorded in Italy, India, and Canada demonstrated strong agreement between predicted and observed outcomes, with a high concordance (CCC = 0.98) and a low average prediction error (RMSE = 0.069). Results suggest that the proposed framework may capture the complexity of the Alternaria-tomato pathosystem and could serve as the basis for a tool to support more informed and sustainable disease management strategies; however, its applicability to mycotoxin risk management remains to be validated. Thu, 01 Jan 2026 00:00:00 GMT https://hdl.handle.net/10807/345145 2026-01-01T00:00:00Z